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Serine protease inhibitor libraries based on natural inhibitor proteins
Reference
E08265
Principal Investigator / Supervisor
Professor Robin Leatherbarrow
Co-Investigators /
Co-Supervisors
Institution
Imperial College London
Department
Chemistry
Funding type
Research
Value (£)
213,573
Status
Completed
Type
Research Grant
Start date
01/08/1998
End date
01/08/2001
Duration
36 months
Abstract
Funding is sought for a project to develop methods that will define the specificity towards inhibition of serine protease enzymes, using a screening approach based on constrained peptide libraries. These methods will allow existing or novel proteases to be quickly mapped in order to define their preferred specificities. The results will provide useful information concerning subsequent design of non-peptide based inhibitors.
Summary
unavailable
Committee
Closed Committee - Engineering & Biological Systems (EBS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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