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Probing and optimising immunosensor surfaces at the molecular level
Reference
E05606
Principal Investigator / Supervisor
Professor Martyn Davies
Co-Investigators /
Co-Supervisors
Professor Clive Roberts
,
Professor Saul Tendler
Institution
University of Nottingham
Department
Sch of Pharmacy
Funding type
Research
Value (£)
160,489
Status
Completed
Type
Research Grant
Start date
08/08/1996
End date
08/08/1999
Duration
36 months
Abstract
We propose to employ a new surface analytical instrument conceived and constructed in-house based on the synergy of atomic force microscopy and surface plasmon resonance for the visualisation of individual antigen-antibody interactions and measurement of real-time kinetics in situ on immunoser surfaces. This molecular resolution approach for studying biointeractions at microtitre well surfaces is novel and will allow the development and optimisation of conventional and novel immobilisation procedures to generate active binding sites displaying good specificity. Such advances will increase our understanding of current assay systems and contribute to future technologies.
Summary
unavailable
Committee
Closed Committee - Engineering & Biological Systems (EBS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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