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Physicochemical studies on biocatalysis in organic media
Reference
E03734
Principal Investigator / Supervisor
Professor Peter James Halling
Co-Investigators /
Co-Supervisors
Dr Graeme Bell
,
Dr Barry Moore
Institution
University of Strathclyde
Department
Bioscience
Funding type
Research
Value (£)
435,932
Status
Completed
Type
Research Grant
Start date
29/01/1993
End date
29/07/1997
Duration
54 months
Abstract
To establish physico-chemical principles that can explain and predict the behaviour of biocatalysts (enzymes and whole cells) in reaction systems composed mainly of organic liquids, or related fluids. Thus to provide a sounder basis for the development and optimisation by industry of processes using such media. Specifically, to study: i) methods for the maintenance of optimal catalyst hydration (through thermodynamic water activity, aw); ii) solvent selection and water effects on binding and kinetic constants for biocatalysts; and iii) the structures of protein and non-protein components of the biocatalyst, in relation to catalytic activity.
Summary
unavailable
Committee
Closed Committee - Engineering & Biological Systems (EBS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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