Award details

Iron responsive regulatory networks in Campylobacter jejuni

Reference	D19661
Principal Investigator / Supervisor	Professor Julian Ketley
Co-Investigators / Co-Supervisors
Institution	University of Leicester
Department	Genetics
Funding type	Research
Value (£)	167,701
Status	Completed
Type	Research Grant
Start date	27/10/2003
End date	26/10/2006
Duration	36 months

Abstract

Iron is an essential nutrient for all organisms and it plays a central role in metabolism, oxidative stress defence and global gene regulation. In Campylobacter, we need to understand the mechanisms of the iron-responsive Fur and PerR regulatory system and the role that iron plays in colonisation and virulence. The Fur-PerR system is an excellent model system to use to investigate regulatory networks in C.jejuni and one to which molecular genetic, bioinformatics and functional genomic tools can be applied. The aims of the project are to fully characterise iron-responsive gene regulation in Campylobacter and the promoter elements involved with a view to establishing knowledge led strategies for the control or eradication of Campylobacter. (Joint with grant number 19662).

Summary

unavailable

Committee	Closed Committee - Agri-food (AF)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

Associated awards:

D19662 Iron Responsive regulatory networks in Campylobacter jejuni

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