Award details

Development and testing of gene-silencing and gene-knockout in Agaricus bisporus

Reference	D19266
Principal Investigator / Supervisor	Professor Gary Foster
Co-Investigators / Co-Supervisors	Dr Andrew Bailey, Miss Claire Burns
Institution	University of Bristol
Department	Biological Sciences
Funding type	Research
Value (£)	175,332
Status	Completed
Type	Research Grant
Start date	05/01/2004
End date	04/01/2007
Duration	36 months

Abstract

The UK has a significant role in mushroom production and in mushroom science. The main technical objectives will be the development of gene-silencing and gene-knockout technologies within Agaricus, with the main scientific objectives centred around the role of a serine proteinase during sphorophore senescence and overall during mushroom development. The exact role of the serine proteinase will be studied using strains in which this gene has been silenced or knocked-out using the technology developed within this proposal, in addition to expression profiling using promoter-GFP fusions. The work described in this proposal will benefit the science used in understanding mushroom biology that will filter through to improvements in production.

Summary

unavailable

Committee	Closed Committee - Agri-food (AF)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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