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Genetic modification of plant secondary metabolism: potential for manipulating pest insects and their natural enemies
Reference
D19250
Principal Investigator / Supervisor
Dr John Rossiter
Co-Investigators /
Co-Supervisors
Professor Murray Grant
,
Professor Richard Mithen
,
Dr Glen Powell
Institution
Imperial College London
Department
Biological Sciences
Funding type
Research
Value (£)
295,264
Status
Completed
Type
Research Grant
Start date
01/10/2003
End date
30/09/2007
Duration
48 months
Abstract
Arabidopsis will be transformed with sense constructs for epithiospecifier protein (ESP), di-oxygenase (AOP2) and gene silenced methylthioalkylmalate synthase (MAM1/MAM2) to produce a variety of near-isogenic lines with contrasting glucosinolates and volatile hydrolysis products. These lines will be used to investigate how different glucosinolate side-chain structures and chain lengths, coupled with expression of functional ESP, determine tritropic interactions between plants, insect pests and beneficial natural enemies. The consequences of release of various nitriles and epithionitriles (functional ESP) vs. isothiocyanates (non-functional ESP) will be investigated for important specialist and generalist pest insects. We will also explore the potential of these metabolites in manipulating host exploitation by parasitoids.
Summary
unavailable
Committee
Closed Committee - Agri-food (AF)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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