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Novel self-processing polyprotein systems for co-ordinated expression
Reference
D19068
Principal Investigator / Supervisor
Professor Martin Ryan
Co-Investigators /
Co-Supervisors
Professor Claire Halpin
,
Dr Garry Luke
Institution
University of St Andrews
Department
Biology
Funding type
Research
Value (£)
317,836
Status
Completed
Type
Research Grant
Start date
01/01/2003
End date
28/02/2006
Duration
38 months
Abstract
The improvement of many plant quality traits in agricultural and horticultural production will require the expression of biochemical pathway or hetero-polymeric proteins. Many of these traits are the product of a number of genes. The exploitation of such genome data will require effective technologies for co-ordinated expression, correct cellular localisation and functioning of multiple proteins. Self-processing polyprotein systems have provided a highly successful strategy to express multiple proteins from a single transcription unit thereby (i) avoiding the problems associated with the use of multiple loci and (ii) increasing long-term stability of the expression of the trait. We wish to expand the range of systems available for the plant biotechnologist by characterising and optimising self-processing systems based upon restriction endoproteinases.
Summary
unavailable
Committee
Closed Committee - Agri-food (AF)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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