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Global identification of genes regulated by luxS- based quorum sensing in Salmonella
Reference
D17313
Principal Investigator / Supervisor
Dr Anjam Khan
Co-Investigators /
Co-Supervisors
Institution
Newcastle University
Department
School of Cell and Molecular Biosciences
Funding type
Research
Value (£)
296,979
Status
Completed
Type
Research Grant
Start date
06/01/2003
End date
05/07/2006
Duration
42 months
Abstract
Our knowledge and understanding of the luxS-based quorum sensing system in Salmonella is minimal. Preliminary data obtained from this laboratory has identified phenotypes for Salmonella luxS mutants and these will be investigated further. Genes regulated by luxS in Salmonella will be identified using genome-wide lacZ transcriptional fusions and DNA microarrays. Finally, the role of luxS in virulence and immunity in vivo will be determined.
Summary
unavailable
Committee
Closed Committee - Agri-food (AF)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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