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Mechanism of action of ghrelin on feeding
Reference
D16910
Principal Investigator / Supervisor
Professor Simon Luckman
Co-Investigators /
Co-Supervisors
Institution
The University of Manchester
Department
Life Sciences
Funding type
Research
Value (£)
120,796
Status
Completed
Type
Research Grant
Start date
01/10/2002
End date
01/10/2005
Duration
36 months
Abstract
The newly-discovered peptide, ghrelin, is the most powerful orexigen so-far described. We will test the hypothesis that its effects on feeding are mediated by central neuropeptide Y-ergic pathways. These pathways will be mapped to identify second and third order neurones involved in mediating ghrelin's actions. Due to the relative selectivity of ghrelin compared to neuropeptide Y itself, these studies will provide important insights into specific neuropeptide Y connections involved in feeding and help to unravel the complex brain circuitry involved in appetite and body weight regulation.
Summary
unavailable
Committee
Closed Committee - Agri-food (AF)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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