BBSRC Portfolio Analyser
Award details
Investigating synergy between genotype and behavioural phenotype in the maintenance of energy balance
Reference
D13460
Principal Investigator / Supervisor
Professor Marion Hetherington
Co-Investigators /
Co-Supervisors
Professor Colin Palmer
,
Dr Wendy Wrieden
Institution
University of Dundee
Department
Psychology
Funding type
Research
Value (£)
432,500
Status
Completed
Type
Research Grant
Start date
14/08/2000
End date
17/03/2004
Duration
43 months
Abstract
This project aims to identify a pre-pubertal cohort who may be genetically predisposed to poor energy balance and to assess evidence of synergy between genotype and behavioural phenotype in the control of energy balance. High prevalence of PPARgamma-gene mutations facilitates detection of greater than 60 hetero- and 10 homozygotes by screening 600 children using PCR. These will be compared with matched controls in their ability to energy compensate in test-meal situations, and in their post-meal consumption response. Accurate measures of total energy expenditure (EE) and percentage body fat by doubly labelled water, with precisely-defined measurement of resting EE will define both sides of the energy balance equation and synergy between the fixed and modifiable factors.
Summary
unavailable
Committee
Closed Committee - Agri-food (AF)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
I accept the
terms and conditions of use
(opens in new window)
export PDF file
back to list
new search