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Will genetic engineering have pleiotropic effects that enhance rhizobial fitness?

ReferenceD13193
Principal Investigator / Supervisor Professor Robert Jones
Co-Investigators /
Co-Supervisors
Dr Lance Mytton, Dr Glynis Scott, Professor Leif Skot
Institution Aberystwyth University
DepartmentInst of Biological, Environ & Rural Sci
Funding typeResearch
Value (£) 195,480
StatusCompleted
TypeResearch Grant
Start date 01/02/2001
End date 01/02/2004
Duration36 months

Abstract

A Rhizobium strain transformed with kanamycin resistance and Bacillus thuringiensis endotoxin genes has an increased ability to compete for nodule sites, compared to the parent. We will determine if this is due to pleiotropic or positional effects of the transgenes by comparing a number of independently transformed Rhizobia of the same strain. The relative biosafety of such transgenics will partly depend on whether transformation enhances their fitness. We will therefore investigate the relationship between nodulation and fitness, including a possible cause of variation in these traits. The results will be relevant to both the efficacy and biosafety of these and other genetically modified organisms.

Summary

unavailable
Committee Closed Committee - Agri-food (AF)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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