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Infertility due to gross rearrangements in the porcine genome: problems and solutions
Reference
D12926
Principal Investigator / Supervisor
Professor Darren Griffin
Co-Investigators /
Co-Supervisors
Professor Nabeel Affara
Institution
Brunel University London
Department
Biological Sciences
Funding type
Research
Value (£)
148,292
Status
Completed
Type
Research Grant
Start date
29/05/2000
End date
01/10/2003
Duration
40 months
Abstract
Pigs provide the world with 42 percent of its meat however the efficiency of pig breeding is reduced because of hypoprolific boars. The current sow/boar ratio of 18:1 is likely to rise to 40:1 due to increased use of artificial insemination. Thus in order to prevent the perpetuation of reduced fertility it is critical that hypoprolific boars are identified and eliminated from breeding regimes. We will therefore test the hypotheses that Y chromosome deletions and cryptic chromosome translocations are two leading causes of the infertility in boars. We will develop novel, cost effective and relatively simple screening procedures that will identify these abnormalities as well as the most common cause of boar hypoprolificacy; visible chromosome translocations. These investigations will have direct and substantial financial benefits to the pig breeding industry in the UK and world-wide.
Summary
unavailable
Committee
Closed Committee - Agri-food (AF)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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