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An analysis of the assembly structure and function of the exosporium of Bacillus cereus
Reference
D11666
Principal Investigator / Supervisor
Professor Anne Moir
Co-Investigators /
Co-Supervisors
Institution
University of Sheffield
Department
Molecular Biology and Biotechnology
Funding type
Research
Value (£)
178,376
Status
Completed
Type
Research Grant
Start date
01/09/1999
End date
01/09/2002
Duration
36 months
Abstract
Bacillus cereus is ubiquitous in the environment, and its spores are potential and actual contaminants of food products. The surface layer of the spore, the exosporium, has not been characterised, although it is thought to be important in adhesion. Our recent studies suggest the presence of functional proteins, including a zinc metalloprotease, in the exosporium. In the project, the gene products important in exosporium structure and assembly will be identified by mutation and by cloning and sequencing, and exosporium assembly and function will be explored in specific directed mutants. The results will be of underpinning relevance to control of B. cereus contamination.
Summary
unavailable
Committee
Closed Committee - Agri-food (AF)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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