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Evaluation of cattle immune responses to live attenuated recombinant Salmonella vaccines

ReferenceD11217
Principal Investigator / Supervisor Professor Bernardo Villarreal-Ramos
Co-Investigators /
Co-Supervisors
Professor Christopher Howard
Institution The Pirbright Institute
DepartmentDiv of Immunology Compton
Funding typeResearch
Value (£) 204,545
StatusCompleted
TypeResearch Grant
Start date 06/09/1999
End date 06/09/2002
Duration36 months

Abstract

Salmonella typhimurium aroA-, aroD-, and htrA mutants expressing the gene encoding the non-toxigenic fragment C of tetanus toxin (TetC) will be used to immunise cattle through different routes, i.e. oral, nasal, and subcutaneous. Mucosal, humoral and cellular immune responses to Salmonella antigens and TetC will be evaluated. Correlates will be drawn on the nature of the responses triggered and the route of inoculation.

Summary

unavailable
Committee Closed Committee - Agri-food (AF)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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