Award details

Gastrointestinal adaptation to fats: implications for feeding and obesity

Reference	D07418
Principal Investigator / Supervisor	Dr Stephen French
Co-Investigators / Co-Supervisors	Professor N Read
Institution	University of Sheffield
Department	Division of Clinical Sciences North
Funding type	Research
Value (£)	127,614
Status	Completed
Type	Research Grant
Start date	01/12/1996
End date	01/12/1999
Duration	36 months

Abstract

This project investigates physiological (mainly gastrointestinal) and feeding behaviour changes in human volunteers following adaptation to high fat diets. The project utilises a number of novel techniques to investigate the role of receptor plasticity in these adaptive responses: measurement of gastric emptying, gallbladder contraction and hormonal responses to specific nutrient challenges, forming the basis of the physiological determination while feeding behaviour will be assessed using food diaries and laboratory measures. The location of sites responsible for these adaptive changes forms the first major portion of the work, this is extended to investigate the time course and specificity of responses to different nutrients.

Summary

unavailable

Committee	Closed Committee - Agri-food (AF)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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