Award details

Investigation of the physiological mechanisms modulating fat-induced satiation and satiety in man

Reference	D06455
Principal Investigator / Supervisor	Professor Linda Morgan
Co-Investigators / Co-Supervisors	Professor Peter Rogers, Professor Nicholas Spyrou
Institution	University of Surrey
Department	Health and Medical Sciences
Funding type	Research
Value (£)	258,643
Status	Completed
Type	Research Grant
Start date	01/10/1996
End date	01/10/1999
Duration	36 months

Abstract

This project investigates the roles played by the gastrointestinal hormones GLP- 1, CCK and GIP in regulating gastric emptying and satiety following nutrient ingestion in man. A tripartite approach combines assessment of satiety in response to dietary fat together with measurement of hormone secretion and gastric emptying. The hypothesis that GIP-1 together with CCK are involved in the induction of satiety will be tested by GLP-1 infusion and CCK receptor antagonist studies. The potential of selective amino acid supplementation to enhance the satiating effect of low-fat meals will also be investigated. As well as advancing basic science in this area, the work has implications for human health and the development of novel food products.

Summary

unavailable

Committee	Closed Committee - Agri-food (AF)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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