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Functional characterisation of the pathogenicity gene MPG1 from the rice blast fungus Magnaporthe grisea

Reference	D01550
Principal Investigator / Supervisor	Professor Nicholas Talbot
Co-Investigators / Co-Supervisors
Institution	University of Exeter
Department	Biosciences
Funding type	Research
Value (£)	156,688
Status	Completed
Type	Research Grant
Start date	15/08/1994
End date	15/08/1997
Duration	36 months

Abstract

The aim of this project is to determine the function of a pathogenicity gene, MPG1, recently cloned from the ascomycete pathogen Magnaporthe grisea. MPG1 encodes a fungal hydrophobin and Mpgl-null mutants show reduced pathogenicity on rice and a dramatic reduction in the frequency of appressorium formation. The function of MPG1 will be determined by three experimental strategies. First, reporter gene fusions will be used to show the temporal and spatial expression of the gene during pathogenesis. Second, the MPG1 gene product will be identified and the timing and location of its accumulation during appressorial morphogenesis determined. Finally, cross-species complementation experiments will be carried out to identify functional homologues of MPG1.

Summary

unavailable

Committee	Closed Committee - Agri-food (AF)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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