Award details

Recombinant plant enzymes for biotransformation processes to make natural flavour chemicals

Reference	CS05294
Principal Investigator / Supervisor	Professor Neil Bruce
Co-Investigators / Co-Supervisors	Professor James Murray
Institution	University of Cambridge
Department	Institute of Biotechnology
Funding type	Research
Value (£)	144,881
Status	Completed
Type	Research Grant
Start date	01/09/1995
End date	01/09/1998
Duration	36 months

Abstract

This project aims to exploit recombinant plant enzymes in a biotransformation process for the production of natural flavours. The project will focus on the cloning and expression of the structural genes of alfalfa hydroperoxide-lysases. A subcloning strategy will be adopted whereby lipooxygenase and hydroperoxide-lyase are expressed in a suitable host organism. This recombinant organism will, theoretically, be capable of converting long chain fatty acids to short chain mono-unsaturated aldehydes. Time permitting, this approach will be directed to extending the recombinant pathway to produce natural flavour alcohols by the expression of an appropriate alcohol dehydrogenase.

Summary

unavailable

Committee	Closed Committee - Engineering & Biological Systems (EBS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Clean Synthesis - CPD (CS) [1995]
Funding Scheme	X – not Funded via a specific Funding Scheme

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