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Comparative development genetics of the ecdysozoa: Tardigrades

Reference	COD17089
Principal Investigator / Supervisor	Professor Mark Blaxter
Co-Investigators / Co-Supervisors	Professor Michael Akam
Institution	University of Edinburgh
Department	Inst of Cell, Animal and Population Biol
Funding type	Research
Value (£)	516,456
Status	Completed
Type	Research Grant
Start date	01/06/2002
End date	31/08/2005
Duration	39 months

Abstract

Tardigrades (water bears) have characters reminiscent of both arthropods (segmentation, limbs) and nematodes (pharynx, eutely). The Ecdysozoa hypothesis links these phyla in a supertaxon of moulting animals, suggesting that the divergent developmental mechanisms of C. elegans and D. melanogaster may derive from an ancestor more recent that their separation from other major lineages. We will perform detailed genomic, developmental biology and developmental genetic analysis (transferring methods from fly and worm fields) in a tardigrade species, Isohypsibius, that we have established in culture. With this data we will compare the evolution of shared and unique features of development in tardigrades, nematodes and arthropods.

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Comparative Development Initiative (COD) [2001]
Funding Scheme	X – not Funded via a specific Funding Scheme

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