Award details

The evolution of vertebrate cranial placodes

Reference	COD16822
Principal Investigator / Supervisor	Professor Sebastian Shimeld
Co-Investigators / Co-Supervisors	Professor Anthony Graham
Institution	University of Reading
Department	Animal and Microbial Sciences
Funding type	Research
Value (£)	204,521
Status	Completed
Type	Research Grant
Start date	01/09/2002
End date	31/01/2005
Duration	29 months

Abstract

Cranial placodes are a key feature of vertebrates, and understanding their evolution is an essential step in understanding the evolution of the complex vertebrate head. At the molecular level placodes are marked by the expression of a number of developmental pathways that, during early vertebrate evolution, were co-opted into placodes to regulate their development. We will investigate how the regulatory pathways controlling placode development have evolved. We will characterise members of these regulatory pathways from basal chordates and examine the evolution of regulatory cis-elements in transgenic ascidian and chick embryos. This will reveal the molecular changes that underlie the evolution of these novel vertebrate characters.

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Comparative Development Initiative (COD) [2001]
Funding Scheme	X – not Funded via a specific Funding Scheme

Associated awards:

COD16822/2 The evolution of vertebrate cranial placodes

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