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The development evolution of fruiting body size and pattern in social amoebae

ReferenceCOD16760
Principal Investigator / Supervisor Professor Pauline Schaap
Co-Investigators /
Co-Supervisors
Institution University of Dundee
DepartmentCollege of Life Sciences
Funding typeResearch
Value (£) 171,304
StatusCompleted
TypeResearch Grant
Start date 01/07/2002
End date 01/07/2005
Duration36 months

Abstract

We describe a three year project to study the developmental evolution of the Dictyostelids. Our aim is to elucidate the mechanisms which underlie morphological variation across closely related, through morphologically distinct, species. We will specifically concentrate on genes that affect development through the major D. discoideum signalling molecule, cAMP, in order to address the following questions: 1) What is the phylogeny of the Dictyostelids? 2) Are genes that affect size and pattern of developmental structures conserved across the species? 3) How have homologous genes diverged in biochemical function and pattern of expression? and 4) To what extent can these functional changes explain morphological variation across Dictyostelids? (Joint with grant 87/COD16761).

Summary

unavailable
Committee Closed Committee - Genes & Developmental Biology (GDB)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative Comparative Development Initiative (COD) [2001]
Funding SchemeX – not Funded via a specific Funding Scheme
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