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Development of a reverse genetics system for the birnavirus infectious bursal disease virus (IBDV)
Reference
CEL04690
Principal Investigator / Supervisor
Professor Michael Skinner
Co-Investigators /
Co-Supervisors
Institution
The Pirbright Institute
Department
Div of Molecular Biology Pirbright
Funding type
Research
Value (£)
136,484
Status
Completed
Type
Research Grant
Start date
01/10/1995
End date
01/10/1998
Duration
36 months
Abstract
We propose to develop a reverse genetics system for the chicken birnavirus, infectious bursal disease virus, using fowlpox virus vectors. The system will be applicable to other segmented and non-segmented RNA viruses and will allow: the study of replication and assembly, the identification of hypervirulence mutation(s) in a recently emerged IBDV variant, which we have sequenced, and the rapid development of new vaccines in response to future threats.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
Cells RoPA (CELL) [1994]
Funding Scheme
X – not Funded via a specific Funding Scheme
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