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Award details
Development of a live antigen delivery system to generate mucosal immunity in the pig
Reference
CEL04595
Principal Investigator / Supervisor
Professor Andrew Rycroft
Co-Investigators /
Co-Supervisors
Institution
Royal Veterinary College
Department
Pathology and Pathogen Biology
Funding type
Research
Value (£)
119,057
Status
Completed
Type
Research Grant
Start date
01/06/1996
End date
01/06/1999
Duration
36 months
Abstract
This project will investigate the use of commensal bacteria for the delivery of foreign antigen to the respiratory mucosa of the pig. Bacteria which naturally colonise the porcine tonsil and which can be genetically manipulated, will be directed to express and secrete recombinant protein using apxlll operon. The potential of an organism to generate a mucosal immune response by sustained secretion of foreign antigen onto lymphoid tissue will be examined.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
Cells RoPA (CELL) [1994]
Funding Scheme
X – not Funded via a specific Funding Scheme
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