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Far-reaching regulators which control the growth of a pathogenic fungus
Reference
CEL04563
Principal Investigator / Supervisor
Professor Al Brown
Co-Investigators /
Co-Supervisors
Institution
University of Aberdeen
Department
School of Medical Sciences
Funding type
Research
Value (£)
135,289
Status
Completed
Type
Research Grant
Start date
06/03/1996
End date
06/03/1999
Duration
36 months
Abstract
We predict that in the pathogenic fungus Candida albicans, the decision to develop a new bud or hypha is taken in the G1 phase of the cell division cycle at START, and that negative regulators of p34/cyclins (analogous to the Saccharomyces cerevisiae FAR1 gene) are critical in this process. Therefore, in this project we will isolate such negative regulators from C. albicans using a genetic screen in S. cerevisiae, and characterise them with respect to their roles in hyphal development in C. albicans.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
Cells RoPA (CELL) [1994]
Funding Scheme
X – not Funded via a specific Funding Scheme
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