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Phage antibodies to surface epitopes of Phytophthora: towards a novel resistance strategy
Reference
CEL04546
Principal Investigator / Supervisor
Dr DJ Nichols
Co-Investigators /
Co-Supervisors
Institution
University of Leicester
Department
Medicine - Pathology
Funding type
Research
Value (£)
129,624
Status
Completed
Type
Research Grant
Start date
15/01/1996
End date
15/01/1999
Duration
36 months
Abstract
Amongst the epitopes exposed on cell surfaces will be those important in cell-cell interactions, such as those that occur during pathogen-host interaction. Antibodies against surface epitopes of Phytophthora germlings will be selected from a phage-displayed immune repertoire. Individual antibodies will be characterised and screened for effects on Phytophthora and on its interactions with its host. This may lead to development of novel resistance strategies and to the identification of pathogenesis factors/targets for chemical control.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
Cells RoPA (CELL) [1994]
Funding Scheme
X – not Funded via a specific Funding Scheme
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