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Award details
Identification and characterisation of targets for insecticidal proteins expressed in transgenic plants
Reference
CEL04531
Principal Investigator / Supervisor
Professor John Gatehouse
Co-Investigators /
Co-Supervisors
Institution
Durham University
Department
Biological and Biomedical Sciences
Funding type
Research
Value (£)
164,225
Status
Completed
Type
Research Grant
Start date
01/12/1995
End date
01/12/1998
Duration
36 months
Abstract
Basic research, employing biochemical and molecular biological techniques, on insect gut proteins and their response to ingested protease inhibitors is proposed in order to generate new and improved methods for engineering plants to enhance their resistance against insect attack. cDNA libraries from gut tissues of larvae of the lepidopteran pest Helicoverpa armigera fed on control and transgenic protease inhibitor-expressing potato will be constructed. Conventional and differential screening of these libraries will be used to isolate and characterise cDNA species which will identify new targets for insecticidal proteins, and will allow novel designer insecticidal proteins to be constructed.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
Cells RoPA (CELL) [1994]
Funding Scheme
X – not Funded via a specific Funding Scheme
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