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The role of cortical microtubules in the regulation of cellulose synthesis

Reference	C19282
Principal Investigator / Supervisor	Professor Simon Turner
Co-Investigators / Co-Supervisors	Dr John Gardiner
Institution	The University of Manchester
Department	Life Sciences
Funding type	Research
Value (£)	248,416
Status	Completed
Type	Research Grant
Start date	01/12/2003
End date	31/12/2006
Duration	37 months

Abstract

A variety of evidence has demonstrated that in plant cells cortical microtubules regulate the orientation of cellulose microfibril synthesis and this in turn regulates the direction of cell expansion. Since our recent cloning of cellulose synthase complex genes we are in a position to determine how microtubules regulate cellulose deposition and how the microtubules themselves are positioned. A system will be developed for monitoring and manipulating cortical microtubules in developing xylem. This will be used in conjunction with GFP fusion with cellulose synthase components to specifically address what regulates microtubule positioning and how in turn this controls the orientation of cellulose synthesis.

Summary

unavailable

Committee	Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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