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Membrane biogenesis in cyanobacteria

Reference	C18608
Principal Investigator / Supervisor	Professor Colin Robinson
Co-Investigators / Co-Supervisors	Professor Conrad Mullineaux
Institution	University of Warwick
Department	Biological Sciences
Funding type	Research
Value (£)	204,608
Status	Completed
Type	Research Grant
Start date	01/10/2003
End date	30/09/2006
Duration	36 months

Abstract

Cyanobacteria exhibit a highly organised form of membrane differentiation in which the plasma and thylakoid membranes carry out specialised roles, yet very little is known about the mechanisms that underpin this compartmentation. We recently succeeded in imaging the transport of green fluorescent protein in Synechocystis PCC6803, and found that it targeted only to the periplasm. We propose to build on this result and analyse the sorting of newly- synthesised proteins in detail. We will (a) identify the signals that direct proteins to the thylakoid lumen, (b) determine whether the lumen connects with the periplasm directly or by vesicle transport, and (c) characterise the sorting of membrane proteins between the plasma and thylakoid membranes.

Summary

unavailable

Committee	Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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