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Measurements of associations and mobility of cell surface receptors by single particle fluorescence imaging

ReferenceC11167
Principal Investigator / Supervisor Professor Richard Cherry
Co-Investigators /
Co-Supervisors
Professor Nelson Fernández
Institution University of Essex
DepartmentBiological Sciences
Funding typeResearch
Value (£) 56,726
StatusCompleted
TypeResearch Grant
Start date 01/03/1999
End date 01/03/2002
Duration36 months

Abstract

Single particle fluorescence imaging (SPFI) is a technique for visualising individual cell surface receptors. The aim of the project is to further develop the methodology using an advanced fluorescence imaging system with improved time-resolution and sensitivity. The new system will be used: a) for detailed studies of the movements of cell surface receptors; b) to enhance existing BBSRC-funded studies of MHC Class II molecules; c) to develop a co- localisation method for detecting receptor associations.

Summary

unavailable
Committee Closed Committee - Biochemistry & Cell Biology (BCB)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative BioImaging (BI) [1998]
Funding SchemeX – not Funded via a specific Funding Scheme
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