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Cyanobacterial homologues of the delta-pH- dependant pathway of chloroplast protein translocation
Reference
C09894
Principal Investigator / Supervisor
Professor Christopher Howe
Co-Investigators /
Co-Supervisors
Institution
University of Cambridge
Department
Biochemistry
Funding type
Research
Value (£)
191,742
Status
Completed
Type
Research Grant
Start date
01/12/1998
End date
01/12/2001
Duration
36 months
Abstract
The aim of the work is to characterise the cyanobacterial protein translocation pathway(s) homologous to the pH-dependent pathway of chloroplasts. The cyanobacterium Synechocystis sp.PCC6803 has two genes encoding proteins homologous to a component of the chloroplast pathway. The genes will be disrupted and effects on protein targeting assessed by 2D gel analysis of cell fractions. The features responsible for any specificity will be assessed by domain-swap experiments. Distribution of the homologues between cyanobacterial membranes will be assessed immunochemically.
Summary
unavailable
Committee
Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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