BBSRC Portfolio Analyser
Award details
The structure and mechanism of catalysis of the photosynthetic water oxidising complex
Reference
C09203
Principal Investigator / Supervisor
Professor J Nugent
Co-Investigators /
Co-Supervisors
Professor M Evans
Institution
University College London
Department
Genetics Evolution and Environment
Funding type
Research
Value (£)
185,750
Status
Completed
Type
Research Grant
Start date
03/09/1998
End date
31/10/2001
Duration
38 months
Abstract
Water oxidation by photosystem II of plants, algae and cyanobacteria is the source of reductant for the biosphere and oxygen in the atmosphere. Water oxidation is catalysed by a Mn complex which accumulates oxidising equivalents following the single electron turnover of photosystem II. The detailed structure and mechanism of catalysis of water oxidation by the complex is unknown. Recent work in our laboratory has identified methods for stabilisation and detection by EPR spectroscopy of previously inaccessible redox states of the Mn complex. A programme is proposed using magnetic resonance and X-ray spectroscopy which will determine the characteristics of substrate binding to the Mn complex and definitively identify the oxidation state of Mn during turnover of the complex. A robust model of the catalytic process will be defined.
Summary
unavailable
Committee
Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
I accept the
terms and conditions of use
(opens in new window)
export PDF file
back to list
new search