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Award details
Study of dynamics, stability and function of porin channels by mutagenesis and biophysical measurements
Reference
C04261
Principal Investigator / Supervisor
Professor Jeremy Lakey
Co-Investigators /
Co-Supervisors
Institution
Newcastle University
Department
School of Cell and Molecular Biosciences
Funding type
Research
Value (£)
139,346
Status
Completed
Type
Research Grant
Start date
01/11/1994
End date
31/10/1997
Duration
36 months
Abstract
1. Design and preparation of site-directed mutagenesis of the OmpC porin channel. 2. Investigation of the role of specific side chains in channel dynamics, channel selectivity and protein stability. 3. Measurement of conformational change in the eyelet and other loop regions.
Summary
unavailable
Committee
Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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