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AMP/Snf1-related protein kinases in higher plants: key players in the response to nutritional and environmental stress?
Reference
C04132
Principal Investigator / Supervisor
Professor David Hardie
Co-Investigators /
Co-Supervisors
Institution
University of Dundee
Department
College of Life Sciences
Funding type
Research
Value (£)
137,010
Status
Completed
Type
Research Grant
Start date
01/10/1995
End date
01/07/1999
Duration
45 months
Abstract
A recent convergence of results has suggested that two higher plant protein kinases, defined biochemically by Prof. Hardie, correspond to products of DNAs cloned by Dr Halford, and/or closely related gene products. These are among the first plant protein kinases to be well defined at the biochemical and molecular genetic levels for which a physiological substrate is known. Their similarity to mammalian and yeast protein kinases suggests that they protect cells against nutritional and/or environmental stress by inhibiting biosynthesis and cell division, and by regulating gene expression. These ideas will be tested by analysis of the structure, regulation and expression of the kinases in pea seedlings and other systems.
Summary
unavailable
Committee
Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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