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Cytochrome biosynthesis in Escherichia coli role or the ABC transporter, CydDC

Reference	C02063
Principal Investigator / Supervisor	Professor Robert K Poole
Co-Investigators / Co-Supervisors
Institution	University of Sheffield
Department	Molecular Biology and Biotechnology
Funding type	Research
Value (£)	154,510
Status	Completed
Type	Research Grant
Start date	27/02/1995
End date	27/05/1998
Duration	39 months

Abstract

The cydDC operon encodes an ABC-family membrane transporter required for assembly of the cytochrome bd quinol oxidase and periplasmic cytochromes. The objectives are to: 1. test the hypothesis that the substrate translocated in haem(s), 2. determine the topology of the CydD and CydC proteins in the membrane, 3. determine structure-function relationships by site-directed mutagenesis, and 4. investigate the regulation of expression of the cydDC operon.

Summary

unavailable

Committee	Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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