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Cloning and characterisation of signalling proteins downstream of the auxin binding protein

ReferenceC01225
Principal Investigator / Supervisor Professor Paul Anthony Millner
Co-Investigators /
Co-Supervisors
Institution University of Leeds
DepartmentInst of Molecular & Cellular Biology
Funding typeResearch
Value (£) 167,239
StatusCompleted
TypeResearch Grant
Start date 21/01/1994
End date 31/10/1997
Duration45 months

Abstract

Synthetic peptides corresponding to the C-terminus of Zea auxin binding protein (ABPzml) will be used for identification and affinity isolation of a transmembrane docking protein (ABP-DP1) which will be cloned and expressed in the Baculovirus/sf9 cell system. Interaction of ABPzml and ABP-DP1 will be characterised and downstream elements sought via affinity isolation and contingent replication assay. Signalling events downstream of ABPzml will be probed in vivo via electrophysiological and ion imaging studies on Vicia and Zea guard cells challenged with ABPzml C-terminal peptides.

Summary

unavailable
Committee Closed Committee - Biochemistry & Cell Biology (BCB)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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