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Award details
Novel antibody-like proteins (ALPs) for the detection monitoring and elimination of pollutants in water
Reference
BSW07304
Principal Investigator / Supervisor
Professor Lesley Torrance
Co-Investigators /
Co-Supervisors
Institution
The James Hutton Institute
Department
Division of Pathology
Funding type
Research
Value (£)
175,374
Status
Completed
Type
Research Grant
Start date
01/10/1997
End date
01/04/2001
Duration
42 months
Abstract
This proposal describes new approaches using state-of-the-art immunotechnology to derive novel diagnostic methods for the detection, monitoring and elimination of trace organic pollutants in water. Three models will be used to validate the approach: Cryptosporidium parvum, a pathogenic micro-organism; microcystin-LR, a toxin produced by cyanobacterial blooms, and glyphosate, an agricultural chemical. The project objectives are: (1) To produce reagents (ALPs) by novel in vitro recombinant DNA methods that will detect and identify three pollutants that may contaminate UK water. (2) To devise simple, rapid and sensitive assays that can detect and quantify these pollutants. (3) To evaluate the assays for use in monitoring water treatment processes. (4) To investigate methodology that can be used to incorporate the ALPs in affinity matrices for water purification.
Summary
unavailable
Committee
Closed Committee - Engineering & Biological Systems (EBS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
LINK: Biotreatment of Soil and Water (BSW) [1993-1999]
Funding Scheme
X – not Funded via a specific Funding Scheme
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