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Use of a transgenic model of human prion disease for transmission studies
Reference
BS206013
Principal Investigator / Supervisor
Professor John Collinge
Co-Investigators /
Co-Supervisors
Institution
Imperial College London
Department
Biological Sciences
Funding type
Research
Value (£)
887,552
Status
Completed
Type
Research Grant
Start date
24/11/1995
End date
24/11/1998
Duration
36 months
Abstract
We are funded to develop a transgenic model of human prion disease using mice expressing human prion protein. We can now report initial transmissions of human prion disease to these mice and request supplementary funding for the remaining year of this study to enable us to carry out larger scale transmission work, and extension of funding for a further 3 years. This transmission facility is unique in Europe and now allows us to address a wide range of questions on the human prion diseases and the human species barrier to BSE and scrapie.
Summary
unavailable
Committee
Closed Committee - Agri-food (AF)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
Biology of Spongiform Encephalopathies - Phase 2 (BS2) [1993]
Funding Scheme
X – not Funded via a specific Funding Scheme
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