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Mining knowledge of protein topology - application of inductive logic programming to discover structural principles
Reference
BIF07106
Principal Investigator / Supervisor
Professor Michael Sternberg
Co-Investigators /
Co-Supervisors
Professor Stephen Muggleton
Institution
Cancer Research UK
Department
Laboratory of Biomolecular Modelling
Funding type
Research
Value (£)
131,105
Status
Completed
Type
Research Grant
Start date
19/05/1997
End date
19/05/2000
Duration
36 months
Abstract
The objective is to apply and thereby challenge one approach for data mining to derive new knowledge about protein structure. Specifically we propose to: (1) Establish a database of protein topology and functional encoded in PROLOG; (2) Perform data mining using inductive logic programming (the program PROGOL) to obtain new structural principles; (3) Identify required improvements in PROGOL; (4) Evaluate the utility of the learnt rules for understanding and predicting protein architecture; (5) Disseminate the results via the Web to the biological and computer science communities. The work will be a collaboration between: the Imperial Cancer Research Fund, Oxford University Computing Lab, Glaxo and SmithKline Beecham.
Summary
unavailable
Committee
Not funded via Committee
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
Bioinformatics (BIF) [1995-1997]
Funding Scheme
X – not Funded via a specific Funding Scheme
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