BBSRC Portfolio Analyser
Award details
Tools for comparative genome analysis
Reference
BIF07052
Principal Investigator / Supervisor
Professor Alan Archibald
Co-Investigators /
Co-Supervisors
Institution
The Roslin Institute
Department
Genetics and Genomics
Funding type
Research
Value (£)
108,407
Status
Completed
Type
Research Grant
Start date
16/03/1998
End date
16/03/2001
Duration
36 months
Abstract
The purpose of this project is to develop tools for comparative genome analysis and in particular to examine the contribution of artificial intelligence (AI) approaches. We propose to develop an AI system for establishing and evaluating homology relationships and to deduce whether they are paralogous or orthologous. The system will be a hybrid of knowledge-based (i.e. an Expert System) and adaptive elements trained from an existing knowledge base. Current AI approaches such as Case Based Reasoning and Genetic Algorithms will be evaluated. The system must cope with complex interdependent relationships; it must integrate diverse criteria such as common patterns of gene expression, nucleic acid sequence identity, relative map location and phylogenetic data. The tools will be implemented through The Comparative Animal Genome database (TCAGdb).
Summary
unavailable
Committee
Not funded via Committee
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
Bioinformatics (BIF) [1995-1997]
Funding Scheme
X – not Funded via a specific Funding Scheme
I accept the
terms and conditions of use
(opens in new window)
export PDF file
back to list
new search