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Self-assembling carbohydrate nanotubes

ReferenceBCI06211
Principal Investigator / Supervisor Professor Jon Preece
Co-Investigators /
Co-Supervisors
Institution University of Birmingham
DepartmentSchool of Chemistry
Funding typeResearch
Value (£) 146,911
StatusCompleted
TypeResearch Grant
Start date 01/11/1996
End date 01/11/1999
Duration36 months

Abstract

The recent development at Birmingham of an efficient polycondensation-cycloglycosidation approach for the synthesis of cyclic oligosaccharides will be employed to construct cyclodextrin-like analogues having either alpha-1,4-linked rhamnopyranosidic or mannopyranosidic units with alternating D and L chiralities, as well as with carboxylic acid functions sited on appropriate hydroxyl groups in order to bring about the self-assembly of these derivatised cyclic oligosaccharides through multiple intermolecular hydrogen bond formation involving matching carboxylic acid dimer units.

Summary

unavailable
Committee Closed Committee - Biomolecular Sciences (BMS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative Biological Chemistry Initiative (BCI) [1995]
Funding SchemeX – not Funded via a specific Funding Scheme
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