Award details

Production of recombinant human and animal vaccines from plant materials

Reference	BCE07274
Principal Investigator / Supervisor	Professor Eli Keshavarz -Moore
Co-Investigators / Co-Supervisors	Professor Peter Dunnill
Institution	University College London
Department	Biochemical Engineering
Funding type	Research
Value (£)	198,321
Status	Completed
Type	Research Grant
Start date	01/08/1997
End date	01/10/2000
Duration	38 months

Abstract

This project will establish the biochemical engineering basis for the large-scale processing of recombinant vaccines from plants. The research will use a combination of scale-down approaches to address four major issues which determine process viability: the selection of appropriate conditions for specific extraction without use of solvents, scale-up of the extraction step with due consideration to the control of shear levels to prevent chloroplast contamination, minimisation of process losses due to impaction-induced entrainment of the virus during separation and the attainment of strict biocontainment of the process sequence. Results will be used to develop a process strategy for the recovery of valuable products from plant sources.

Summary

unavailable

Committee	Closed Committee - Engineering & Biological Systems (EBS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	LINK: Biochemical Engineering (BCE) [1993-1997]
Funding Scheme	X – not Funded via a specific Funding Scheme

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