Award details

OpenPlant: University of Cambridge-John Innes Centre for Synthetic Biology

Reference	BBS/E/J/000CA556
Principal Investigator / Supervisor	Professor Anne Osbourn
Co-Investigators / Co-Supervisors	Dr Rob Field, Professor George Lomonossoff, Professor Cathie Martin, Professor Sarah O'Connor, Professor Giles Oldroyd, Dr Paul O'Maille (JIC), Professor Dale Sanders, Professor Alison Smith
Institution	John Innes Centre
Department	John Innes Centre Department
Funding type	Research
Value (£)	1,213,657
Status	Completed
Type	Institute Project
Start date	31/07/2014
End date	31/03/2017
Duration	32 months

Abstract

The OpenPlant Research initiative has been funded with three main aims: 1. to create a hub for interdisciplinary exchange between Cambridge and Norwich, between the fundamental and applied sciences, that will underpin advances in UK agriculture and bioproduction. 2. to establish systems for the open exchange of new plant tools and DNA components that will promote commercial innovation and international scientific exchange. 3. to explore the wider implications of the technology at local and global scales. This will bring together a wide range of engineers, scientists and policy developers to explore new technologies and possible models for sustainable agriculture, bioproduction and land use. As part of the OpenPlant initiative, we will implement technologies for engineering plants: • Open DNA registries for sharing information, and join an international web of registries with the first plant specific parts. • A major new plant chassis for Synthetic Biology, with simple properties for high throughput screening and analysis at the micron scale. • New DNA parts for the control and quantitative imaging of genetic circuits in plants. • Techniques for routine genome-scale engineering in plants. • Software tools with improved performance for automated DNA assembly, modeling of synthetic gene circuits and cellular morphogenesis. The development of new tools and parts will directly contribute to the engineering of new traits in plants, such as: • Altered photosynthesis and leaf structure. • Changes in plant carbohydrate content. • Engineered pathways for the metabolic engineering of natural products. • New forms of symbiosis and nitrogen fixation for crop plants. • Methods for high level production of biomolecules by transient expression

Summary

unavailable

Committee	Not funded via Committee
Research Topics	Industrial Biotechnology, Plant Science, Synthetic Biology
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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