BBSRC Portfolio Analyser
Award details
Molecular mechanisms regulating follicle growth in cattle
Reference
BBS/E/R/03780670
Principal Investigator / Supervisor
Dr David Armstrong
Co-Investigators /
Co-Supervisors
Institution
The Roslin Institute
Department
The Roslin Institute Department
Funding type
Research
Value (£)
118,196
Status
Completed
Type
Institute Project
Start date
01/04/2002
End date
31/03/2006
Duration
48 months
Abstract
Understanding mechanisms regulating folliculogenesis is a key aspect in the design of procedures for regulating animal production systems. This programme of work addresses this issue by providing information on molecular mechanisms regulating two key events in the life of a follicle, namely the initial recruitment of a primordial follicle into the growing pool and the selection of a dominant follicle. Genes involved in regulating these events will be identified using DNA microarrays and PCR based cDNA subtraction libraries. Once identified the genes will be characterised by in situ hybridization and the regulation of their expression examined in primary cultures of granulosa and theca cells. The identification of new genes regulating folliculogenesis is a central theme of this proposal, their identification will open up opportunities for the development of novel technologies for controlling reproduction.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
I accept the
terms and conditions of use
(opens in new window)
export PDF file
back to list
new search