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The theory and practice of QTL mapping and marker assisted selection

ReferenceBBS/E/R/02780640
Principal Investigator / Supervisor Professor Christopher Haley
Co-Investigators /
Co-Supervisors
Institution The Roslin Institute
DepartmentThe Roslin Institute Department
Funding typeResearch
Value (£) 116,126
StatusCompleted
TypeInstitute Project
Start date 01/04/1998
End date 31/03/2002
Duration48 months

Abstract

Genetic maps of the major livestock species are now sufficiently densely populated with polymorphic markers to enable low resolution scanning the complete genomes for loci controlling variation in quantitative traits (quantitative trait loci or QTLs). The basis of the approach is the detection of an association between observable segregation at a genetic marker and phenotypic performance. However, extracting the maximum information from the data requires careful experimental design and powerful and robust methods of statistical analysis. Additionally, mapping and exploiting quantitative trait loci (QTLs) in livestock is made challenging by the potential complexities of the pedigrees involved and by the fact that markers are not informative in all individuals.

Summary

unavailable
Committee Closed Committee - Genes & Developmental Biology (GDB)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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