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Genetic Dissection of Ascites in Chickens

Reference	BBS/E/R/00003709
Principal Investigator / Supervisor	Professor Christopher Haley
Co-Investigators / Co-Supervisors
Institution	The Roslin Institute
Department	The Roslin Institute Department
Funding type	Research
Value (£)	1,300
Status	Completed
Type	Institute Project
Start date	01/10/2006
End date	30/09/2009
Duration	36 months

Abstract

Ascites, the accumulation of fluid in the peritoneum, is one of the most significant metabolic conditions affectingbroiler chicken production and is partly under gentic control. This project combines quantitave genetic and genomic tools to dissect this trait. Using data from a SNP based screen of Aviagen's populations we will attempt to identify candidate genome regions and genes associated with suscepttibilty to Ascites. Prior to the start of the project preliminary analysis will have been performed by Aviagen on the data from the SNP screen. The project comprises: 1/ Confirming SNP associations and prediction of parental ascites genotypes. 2/ Confirming SNP associations is sires in independant samples and performing within family linkage analysis. 3/ Exploring potential candidate genes underlying detected associations/linkages for causative polymorphisms.4/ testing identified causative SNPs in other populations. Together these components will throw light on the gentic control of ascites and the potential for marker-assisted reduction of susceptibilty to this condition.

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	Animal Health
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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