Award details

Transgenic chicken facility

Reference	BBS/E/R/00001611
Principal Investigator / Supervisor	Professor Helen Sang
Co-Investigators / Co-Supervisors
Institution	The Roslin Institute
Department	The Roslin Institute Department
Funding type	Research
Value (£)	24,129
Status	Completed
Type	Institute Project
Start date	01/04/2007
End date	31/05/2007
Duration	2 months

Abstract

Background: The development of the use of lentiviral vectors has reached a stage where the technology has the potential to be used by several groups within Roslin and in collaborations with a large number of external groups. The current technology is complicated and requires a wide range of skills, from construction and packaging of lentiviral vectors, through chick embryo microinjection and culture, to artificial insemination for breeding and pedigree hatching and screening of many chicks per week. The technology is still being developed, for example to increase efficiency, and the current resources are also used to support experiments that require chick embryo material and manipulation of embryos in ovo. Purpose The purpose of this proposal is to exploit the technology developed at Roslin and the unique facilities that enabled this development, to generate high quality research and establish Roslin as a centre for experimentation in the chick, in areas as diverse as development and disease, with links to our complementary expertise in chick genomics. Proposal The proposal is that a basic resource be supported from core funds to facilitate usage of the technology. Users will then be able to buy access to a package of support provided by the facility. The current proposal is that a core of staff be allocated to the transgenic chicken facility: Dr Adrian Sherman (to manage group and carry out transgenic production and screening), Mrs Rhona Mitchell and Ms Frances Thomson to support the transgenic production and carry out experimental work within the Poultry Unit. Additional technical input is required to run the process effectively.

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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