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Award details
Dynamics of mean gain and variance analysis
Reference
BBS/E/R/00001610
Principal Investigator / Supervisor
Professor John Woolliams
Co-Investigators /
Co-Supervisors
Institution
The Roslin Institute
Department
The Roslin Institute Department
Funding type
Research
Value (£)
118,428
Status
Completed
Type
Institute Project
Start date
01/04/2007
End date
31/03/2011
Duration
48 months
Abstract
The proposed research in quantitative genetics is concerned with genetic change (?G) and associated risks, such as introducing genetic diseases, related to the rate of inbreeding (?F). The approach taken will be to exploit the concept of a long-term genetic contribution of an ancestor that has been largely developed in our laboratory. It has provided a unifying concept and provided solutions to many long-standing genetic problems. The issues addressed will be: near-random mating where the benefits of mating will be combined into two weighted components corresponding to prospective and retrospective actions; improved operational tools (including markers) that exploit the results from the near random mating; linked gene flow to underpin improved linkage disequilibrium methods; and improved predictions for non-random mating and exponential contribution models.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
Animal Health
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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