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Award details
Disease genetics a multi-disciplinary approach
Reference
BBS/E/R/00000691
Principal Investigator / Supervisor
Professor Stephen Bishop
Co-Investigators /
Co-Supervisors
Institution
The Roslin Institute
Department
The Roslin Institute Department
Funding type
Research
Value (£)
198,903
Status
Completed
Type
Institute Project
Start date
01/04/2005
End date
31/03/2009
Duration
48 months
Abstract
The study of host-parasite interactions and the devlopment of genetic stratagies to help control infectious diseases is a major focus of Roslin Institute's research stratagy. This proposal describes work aimed at elucidating host genetic factors controlling response to a variety of diseases of importance to UK livestock industries and developing the theory and tools necessary to predict the consequences of genetic improvement of disease resistance. Together, this research should make a major contribution to the disease genetics portfolio at Roslin Institute. The specific objectives are: (1) to coordinate disease genetics research at Roslin Institute and also at the national and European levels: (2) to undertake experimental and field studies in disease genetics, particularly in nematode infections and scrapie resistance in sheep, in PRRS resistance in pigs, inIPN resistance in salmon, and in components of innate immunity in pigs; and (3) to advance and refine genetic-epidemiological modeling technoques. This last objective will inclide the further development of existing theory for both micro- and macroparasitic infections, refining models of nematode resistance in sheep that include host nutrition and immunity, and developing at least one new genetic-epidemiological models for a disease of economic importance.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
Animal Health, Immunology, Microbiology
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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