BBSRC Portfolio Analyser
Award details
Host response/ Disease resistance traits in cattle
Reference
BBS/E/R/00000686
Principal Investigator / Supervisor
Professor Elizabeth Glass
Co-Investigators /
Co-Supervisors
Institution
The Roslin Institute
Department
The Roslin Institute Department
Funding type
Research
Value (£)
940,002
Status
Completed
Type
Institute Project
Start date
01/04/2004
End date
31/03/2008
Duration
48 months
Abstract
My role is to coordinate and manage a portfolio of research projects on the genetics and genomics of livestock immunity and disease resistance. The aim of the CSG programme is to focus on two major themes. First, by exploiting the Roslin Institute RoBoGen herd, QTL for immune traits will be mapped. Uniquely the interactions between genes controlling immune response and genes controlling performance traits will be investigated in cattle. Second, the genetic basis for breed differences in resistance to a protozoan parasite of cattle will be explored. Current evidence suggests that macrophage control of cytokine production is the key. Phenotypic and functional differences in macrophages from both breeds will be investigated using a variety of approaches, exploiting a bovine immune-focused microarray, developed in an externally funded grant.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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