BBSRC Portfolio Analyser
Award details
Molecular mechanisms that reprogramme nuclei early in mammalian development and their importance for animal well being
Reference
BBS/E/R/00000683
Principal Investigator / Supervisor
Professor Ian Wilmut
Co-Investigators /
Co-Supervisors
Institution
The Roslin Institute
Department
The Roslin Institute Department
Funding type
Research
Value (£)
294,771
Status
Completed
Type
Institute Project
Start date
01/04/2004
End date
31/03/2008
Duration
48 months
Abstract
Epigenetic mechanisms act throughout life to regulate gene expression. This programme of research will use molecular and nuclear transfer techniques to investigate epigenetic mechanisms that regulate early mammalian embryo development and use the new understanding in biomedical research. Specifically we will analyse the function of oocyte specific methyl transferase and other genes shown to be essential for normal development and examine the relationship between chromatin organisation in donor cells and early embryos and their developmental potential. Understanding of these epigenetic mechanisms is important for improvement of human and animal health, and will also create a variety of new biomedical opportunities
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
I accept the
terms and conditions of use
(opens in new window)
export PDF file
back to list
new search